Journal: Mayo Clinic Proceedings

Article Title: Mental Stress and Its Effects on Vascular Health

doi: 10.1016/j.mayocp.2022.02.004

Figure Lengend Snippet: Summary of All Published Prospective Cohort Studies Evaluating the Relationship Between Experimentally Induced Mental Stress and Cardiovascular Outcomes, in Addition to Measurements of a Putative Mediating Pathologic Mechanism a

Article Snippet: , 2011 , 25 (6) , Healthy subjects , Three different MS tasks of 6-min duration in random order (number-letter recall challenge of increasing length and complexity; number subtraction; Stroop word-color conflict) , RH-PAT at baseline (baseline PEF) compared with RH-PAT following MS (post-MS PEF) , Arterial blood pressure signal amplitude using cuff attached to a pressure transducer (BIOPAC MP150 systems technology — a standard polygraph device used to detect deception during polygraph examinations in military or law enforcement applications) , No significant difference in RH-PAT and BIOPAC arterial blood pressure signal amplitude at rest or following MS (1.55±0.36 and 1.48±0.19; P =.38 and 1.44±0.29 and 1.47±0.21; P) =.61, respectively) , Lower stress PAT ratio vs BIOPAC stress ratio during each of the 3 MS tasks.

Techniques: Modification, Clinical Proteomics, Imaging, Medications, Functional Assay, Activation Assay

Journal: Mayo Clinic Proceedings

Article Title: Mental Stress and Its Effects on Vascular Health

doi: 10.1016/j.mayocp.2022.02.004

Figure Lengend Snippet: Summary of All Published Cross-Sectional Studies Evaluating the Relationship Between Experimentally Induced Mental Stress and Peripheral Vascular Reactivity a

Article Snippet: , 2011 , 25 (6) , Healthy subjects , Three different MS tasks of 6-min duration in random order (number-letter recall challenge of increasing length and complexity; number subtraction; Stroop word-color conflict) , RH-PAT at baseline (baseline PEF) compared with RH-PAT following MS (post-MS PEF) , Arterial blood pressure signal amplitude using cuff attached to a pressure transducer (BIOPAC MP150 systems technology — a standard polygraph device used to detect deception during polygraph examinations in military or law enforcement applications) , No significant difference in RH-PAT and BIOPAC arterial blood pressure signal amplitude at rest or following MS (1.55±0.36 and 1.48±0.19; P =.38 and 1.44±0.29 and 1.47±0.21; P) =.61, respectively) , Lower stress PAT ratio vs BIOPAC stress ratio during each of the 3 MS tasks.

Techniques: Tandem Mass Spectroscopy, Saline, Clinical Proteomics, Activity Assay, Activation Assay, Control, Imaging

Journal: Mayo Clinic Proceedings

Article Title: Mental Stress and Its Effects on Vascular Health

doi: 10.1016/j.mayocp.2022.02.004

Figure Lengend Snippet: Outline of the various mechanisms by which stress pathologically affects vascular health (in boxes), and biomarkers available to measure these effects. CBF, coronary blood flow; CRP, C-reactive protein; DBP, diastolic blood pressure; FMD, flow-mediated dilatation; H-P-A axis, hypothalamic-pituitary-adrenal axis; HR, heart rate; IL, interleukin; LV, left ventricular; MS, mental stress; MSIMI, mental stress induced myocardial ischemia; NF-κβ; nuclear factor kappa light chain enhancer of activated B cells; PP, pulse pressure; RH-PAT, reactive hyperemia – peripheral arterial tonometry; SBP, systolic blood pressure; SVR, systemic vascular resistance; TNF, tumor necrosis factor.

Article Snippet: , 2011 , 25 (6) , Healthy subjects , Three different MS tasks of 6-min duration in random order (number-letter recall challenge of increasing length and complexity; number subtraction; Stroop word-color conflict) , RH-PAT at baseline (baseline PEF) compared with RH-PAT following MS (post-MS PEF) , Arterial blood pressure signal amplitude using cuff attached to a pressure transducer (BIOPAC MP150 systems technology — a standard polygraph device used to detect deception during polygraph examinations in military or law enforcement applications) , No significant difference in RH-PAT and BIOPAC arterial blood pressure signal amplitude at rest or following MS (1.55±0.36 and 1.48±0.19; P =.38 and 1.44±0.29 and 1.47±0.21; P) =.61, respectively) , Lower stress PAT ratio vs BIOPAC stress ratio during each of the 3 MS tasks.

Techniques:

Journal: American Journal of Physiology - Regulatory, Integrative and Comparative Physiology

Article Title: Active and passive heat stress similarly compromise tolerance to a simulated hemorrhagic challenge

doi: 10.1152/ajpregu.00199.2014

Figure Lengend Snippet: Core and skin temperatures before and during lower body negative pressure (LBNP) to presyncope in all conditions. Mean skin and core body temperatures increased with all methods of heat stress before LBNP. However, by design, mean skin temperatures were higher after passive heat stress and active 38 (∼38°C, active 38) trials compared with active 36 (36°C, active 36) (both P ≤ 0.05), and remained higher throughout LBNP to presyncope. At presyncope, mean skin temperature was unchanged (P > 0.05), whereas core temperature was slightly elevated in the passive heat stress and active 38 trials. Data are means ± SD at baseline, immediately before LBNP (pre-LBNP), throughout LBNP at 20, 40, 60, and 80% of maximal cumulative stress index (CSI), and at presyncope. *Different from baseline in all trials (P ≤ 0.05). #Different from pre-LBNP in passive heat stress and active 38 trials only (P ≤ 0.05). λDifferent from active 36 (P ≤ 0.05).

Article Snippet: Throughout LBNP, arterial blood pressures were also measured at the brachial artery by auscultation (Tango, Suntech Medical Instruments, Raleigh, NC).

Techniques:

Journal: American Journal of Physiology - Regulatory, Integrative and Comparative Physiology

Article Title: Active and passive heat stress similarly compromise tolerance to a simulated hemorrhagic challenge

doi: 10.1152/ajpregu.00199.2014

Figure Lengend Snippet: Heart rate and blood pressure responses before and during LBNP to presyncope in all conditions. When expressed relative to a percentage of maximal CSI, heart rate and mean arterial pressure were not different between trials at any point. In all trials, blood pressure and heart rate decreased at presyncope relative to 80% CSI. Data are means ± SD at baseline, immediately before LBNP (pre-LBNP), throughout LBNP at 20, 40, 60, and 80% of maximal CSI and at presyncope. *Different from baseline in all trials (P ≤ 0.05). §Different from 80% CSI in all trials (P ≤ 0.05).

Article Snippet: Throughout LBNP, arterial blood pressures were also measured at the brachial artery by auscultation (Tango, Suntech Medical Instruments, Raleigh, NC).

Techniques: